Viagra shocking effect on blood cancer treatment

Viagra is widely known for the treatment of erectile dysfunction.it is a drug that has changed many lives of men around the world over the past few years.

According to research, viagra could have a larger side effect that scientists never knew about and one that could save lives.

Commonly used treatment for blood cancer

The most common treatment for blood cancer is the use of blood stem cell transplants. They are used to treat leukemia, but also for various conditions. Before having cancer chemotherapy sometimes patients do donate their blood stem cells and then have them taken back in later. But most of the time the blood stem cells are donated by other people either family or friends.

Hematopoietic stem cells (HSCs) can help to cure cancer. But a problem that needs to be overcome is that of harvesting them for transplantation. According to research is not an easy process to harvest blood stem cells. For donors to donate stem cell they must be given a dose of G-CSF this will help them increase the level of blood stem cells. It will help in the stimulation of the bone marrow where blood stem cells are produced and stored. Then ready for an easy collection.

Sadly, G-CSF can result in side effects on donors such as :

  • Nausea
  • Bone pain
  • fatigue

It’s also not recommended for patients who have a history of being in chemotherapy or those that are elderly, frail.

According to the research done by the University of California in Santa Cruz, they may have come up with an unexpected solution to solve this problem. A test performed by the University of California in Santa Cruz involved two of the FDA approved drugs which are Viagra, Plerixafor the test involved a mice and the stimulation of blood cells was a success.

Provided that the drugs have been approved by the FDA the process can be tested in humans who are willing to volunteer. This is a process that could help in the preparation of the stem cell transplant. The team came to a conclusion that Plerixafor alone did increase the stem cells but the introduction of viagra alone did highly increase the cell numbers found in the circulation.almost to the level of the mice treated with G-CSF.

There were no side effects on the mice on Viagra combination treatment recorded. That means that if the same was put to test on a human being, blood stem cells for donors could result in a large increase and the process will be cheaper, faster and with no side effects.

Viagra was made to cure cardiovascular diseases and even for pulmonary hypertension. And according to Forsberg lab, they came to a conclusion that reason being that viagra normally causes the relaxation of the vessel walls this could help when it comes to promoting stem cell mobilization.

In mice injected with the Mozobil and a dose of viagra, produced around 2,500 of hematopoietic stem cells to enter the flow of bloodstream in just under 2 hours. In short, viagra alone was not effective. And only the threefold increase was because of Mozobil monotherapy.

According to research done in the Ottawa hospital, found out that a flu vaccine known as seqirus could highly reduce the risk of the spread of cancer this was seen after a post-surgery on a mice.

Forsberg and the team can now work with the clinical teams to try and see how they can advance their findings and try it on humans. The process is to try to have alternatives for G-CSF the process will be more suitable for donors’ reason because they will have no fear of having any side effects.